Influence Sensitivity to Bacterial IgA 1 Sites in the CH 3 Domain of Human IgA

Influence Sensitivity to Bacterial IgA 1 Sites in the CH 3 Domain of Human IgA 1

ISOGEOMETRIC TOPOLOGY OPTIMIZATION OF STRUCTURES USING LEVEL SET METHOD INCORPORATING SENSITIVITY ANALYSIS

This study focuses on the topology optimization of structures using a hybrid of level set method (LSM) incorporating sensitivity analysis and isogeometric analysis (IGA). First, the topology optimization problem is formulated using the LSM based on the shape gradient. The shape gradient easily handles boundary propagation with topological changes. In the LSM, the topological gradient method as ...

Immunoglobulin A Preparation from Human Pooled Plasma Using Plasma Fractionation and Ion Exchange Chromatography

Background: In this study we have prepared the IgA solution from normal human plasma using plasma fractionation and ion exchange chromatography. Materials and Methods: Using fractionation of plasma with cold ethanol (starting with 8% ethanol), fraction III was prepared as a suitable source for IgA preparation. Then it was treated with caprylic acid for separation of impurities. For enrichm...

Alterations in salivary IgA levels in infectious and inflammatory disorders of upper respiratory tract

Background: The airway surfaces are one of the most common ways of entry of infectious agents. Oral cavity associated lymphoid tissues are inductive site of humoral immune responses in inflammatory and infectious disorders of the upper respiratory tract. These lymphoid tissues play important roles in the induction of salivary IgA. The impact of upper respiratory tract diseases on salivary IgA p...

The Diagnostic Value of Serum IgG-Antigliadin, IgA Anti-endomysial and IgA Anti-tissue Transglutaminase Antibodies for Pediatric Celiac Disease

  Background and Objective: Celiac disease is an autoimmune disorder, characterized by inflammation, villous atrophy, and crypt hyperplasia of the small bowel mucosa. In this study we considered and compared sensitivity and specificity of serological tests in patients with celiac disease. Materials and Methods: In this cross-sectional study we prospectively recruited children with suspected c...